Potent Oxidation of DNA by Haloquinoid Disinfection Byproducts to the More Mutagenic Imidazolone dIz via an Unprecedented Haloquinone-Enoxy Radical-Mediated Mechanism

Author:

Shao Jie1ORCID,Huang Chun-Hua1ORCID,Shao Bo1,Qin Li1,Xu Dan1,Li Feng1,Qu Na1,Xie Lin-Na1,Kalyanaraman Balaraman2ORCID,Zhu Ben-Zhan1ORCID

Affiliation:

1. State Key Laboratory of Environmental Chemistry and Eco-toxicology, Research Centre for Eco-environmental Sciences and University of the Chinese Academy of Sciences, the Chinese Academy of Sciences, Beijing 100085, PR China

2. Department of Biophysics, Medical College of Wisconsin, Milwaukee, Wisconsin 53226, United States

Funder

National Institute of Environmental Health Sciences

National Center for Research Resources

National Natural Science Foundation of China

Chinese Academy of Sciences

Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences

Publisher

American Chemical Society (ACS)

Subject

Environmental Chemistry,General Chemistry

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