5-Alkyl-6-benzyl-2-(2-oxo-2-phenylethylsulfanyl)pyrimidin-4(3H)-ones, a Series of Anti-HIV-1 Agents of the Dihydro-alkoxy-benzyl-oxopyrimidine Family with Peculiar Structure−Activity Relationship Profile-Reference-Cited by-同舟云学术

5-Alkyl-6-benzyl-2-(2-oxo-2-phenylethylsulfanyl)pyrimidin-4(3H)-ones, a Series of Anti-HIV-1 Agents of the Dihydro-alkoxy-benzyl-oxopyrimidine Family with Peculiar Structure−Activity Relationship Profile

Published:2008-07-17 Issue:15 Volume:51 Page:4641-4652
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Nawrozkij Maxim B.¹,Rotili Dante¹,Tarantino Domenico¹,Botta Giorgia¹,Eremiychuk Alexandre S.¹,Musmuca Ira¹,Ragno Rino¹,Samuele Alberta¹,Zanoli Samantha¹,Armand-Ugón Mercedes¹,Clotet-Codina Imma¹,Novakov Ivan A.¹,Orlinson Boris S.¹,Maga Giovanni¹,Esté José A.¹,Artico Marino¹,Mai Antonello¹

Affiliation:

1. Volgograd State Technical University, Pr. Lenina, 28, 400131 Volgograd, Russia, Dipartimento di Studi Farmaceutici, Sapienza Università di Roma, P. le A. Moro 5, 00185 Roma, Italy, Istituto di Genetica Molecolare IGM-CNR, via Abbiategrasso 207, 27100 Pavia, Italy, and Retrovirology Laboratory IrsiCaixa, Hospital Universitari Germans Trias i Pujol, Universitat Autònoma de Barcelona, 08916 Badalona, Spain

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm800340w

Reference59 articles.

1. Selected non-nucleoside reverse transcriptase inhibitors (NNRTIs): The DABOs family

2. Emerging anti-HIV drugs

3. New Approaches toward Anti-HIV Chemotherapy

4. Non-Nucleoside HIV-1 Reverse Transcriptase (RT) Inhibitors: Past, Present, and Future Perspectives

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