Targeting SHP2 with an Active Site Inhibitor Blocks Signaling and Breast Cancer Cell Phenotypes-Reference-Cited by-同舟云学术

Targeting SHP2 with an Active Site Inhibitor Blocks Signaling and Breast Cancer Cell Phenotypes

Published:2023-07-14 Issue:5 Volume:3 Page:418-428
ISSN:2694-2437
Container-title:ACS Bio & Med Chem Au
language:en
Short-container-title:ACS Bio Med Chem Au

Author:

Lade Dhanaji M.¹,Agazie Yehenew M.¹^ORCID

Affiliation:

1. One Medical Center Drive, Department of Biochemistry and Molecular Medicine, School of Medicine, West Virginia University, P.O. Box 9142, Morgantown, West Virginia 26506, United States

Funder

National Cancer Institute

Publisher

American Chemical Society (ACS)

Subject

Pharmaceutical Science,Drug Discovery,Molecular Biology,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acsbiomedchemau.3c00024

Reference38 articles.

1. Concomitant activation of the PI3K-Akt and the Ras-ERK signaling pathways is essential for transformation by the V-SEA tyrosine kinase oncogene

2. Molecular Mechanism for a Role of SHP2 in Epidermal Growth Factor Receptor Signaling

3. The phosphotyrosine phosphatase SHP2 is a critical mediator of transformation induced by the oncogenic fibroblast growth factor receptor 3

4. Modulation of α-catenin Tyr phosphorylation by SHP2 positively effects cell transformation induced by the constitutively active FGFR3

5. Hepatocyte growth factor (HGF) signals through SHP2 to regulate primary mouse myoblast proliferation

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