Enhanced Cancer Cell Growth Inhibition by Dipeptide Prodrugs of Floxuridine: Increased Transporter Affinity and Metabolic Stability
Author:
Affiliation:
1. Department of Pharmaceutical Science, University of Michigan, Ann Arbor, Michigan 48109, and TSRL, Inc., Ann Arbor, Michigan 48108
Publisher
American Chemical Society (ACS)
Subject
Drug Discovery,Pharmaceutical Science,Molecular Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/mp800008c
Reference49 articles.
1. Amino Acid Ester Prodrugs of the Antiviral Agent 2-Bromo-5,6-dichloro-1-(β-d-ribofuranosyl)benzimidazole as Potential Substrates of hPEPT1 Transporter
2. Amino Acid Ester Prodrugs of the Anticancer Agent Gemcitabine: Synthesis, Bioconversion, Metabolic Bioevasion, and hPEPT1-Mediated Transport
3. Synthesis of analogs of l-valacyclovir and determination of their substrate activity for the oligopeptide transporter in Caco-2 cells
Cited by 67 articles. 订阅此论文施引文献 订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献
1. Evaluating physiochemical properties of FDA-approved orally administered drugs;Expert Opinion on Drug Discovery;2023-11-03
2. Synthesis and biological activity assay of novel camptothecin-peptidic conjugates based on PEPT1;Bioorganic & Medicinal Chemistry Letters;2023-11
3. Utilizing Circumcoronene and BN Circumcoronene for the delivery and adsorption of the anticancer drug floxuridine;Computational and Theoretical Chemistry;2023-04
4. Transporter-Mediated Drug Delivery;Molecules;2023-01-24
5. Folic acid grafted aminated zeolitic imidazolate framework (ZIF-8) as pH responsive drug carrier for targeted delivery of curcumin;Journal of Drug Delivery Science and Technology;2023-01
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线，采集、加工和组织学术论文而形成的新型学术文献查询和分析系统，可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容，当前同舟云学术共收录了国内外主流学术期刊6万余种，收集的期刊论文及会议论文总量共计约1.5亿篇，并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询！咨询电话：010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3