Preparation of Acidic 5-Hydroxy-1,2,3-triazoles via the Cycloaddition of Aryl Azides with β-Ketoesters
Author:
Affiliation:
1. Centre for Synthesis and Chemical Biology (CSCB), Department of Chemistry, Royal College of Surgeons in Ireland, 123 St. Stephen’s Green, Dublin 2, Ireland
2. KelAda Pharmachem Ltd., A1.01 Science Centre South, Belfield, Dublin 4, Ireland
Funder
Irish Research Council
Publisher
American Chemical Society (ACS)
Subject
Organic Chemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/acs.joc.1c00778
Reference30 articles.
1. Medicinal attributes of 1,2,3-triazoles: Current developments
2. 1,2,3,-Triazole-Based Catalysts: From Metal- to Supramolecular Organic Catalysis
3. Applications of Metal-Free 1,2,4-Triazole Derivatives in Materials Science
4. A Strain-Promoted [3 + 2] Azide−Alkyne Cycloaddition for Covalent Modification of Biomolecules in Living Systems
5. Evaluation of 1,2,3‐Triazoles as Amide Bioisosteres In Cystic Fibrosis Transmembrane Conductance Regulator Modulators VX‐770 and VX‐809
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3. Three‐Component Reactions of 2,2,2‐Trifluoroethyl Ketones, Aryl Azides and Aqueous Ammonia for the Synthesis of 4‐Cyano‐1,2,3‐triazoles;European Journal of Organic Chemistry;2023-12-18
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