DNA-Targeted 1,2,4-Benzotriazine 1,4-Dioxides: Potent Analogues of the Hypoxia-Selective Cytotoxin Tirapazamine-Reference-Cited by-同舟云学术

DNA-Targeted 1,2,4-Benzotriazine 1,4-Dioxides: Potent Analogues of the Hypoxia-Selective Cytotoxin Tirapazamine

Published:2003-12-17 Issue:2 Volume:47 Page:475-488
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Hay Michael P.¹,Pruijn Frederik B.¹,Gamage Swarna A.¹,Liyanage H. D. Sarath¹,Kovacs Mary S.¹,Patterson Adam V.¹,Wilson William R.¹,Brown J. Martin¹,Denny William A.¹

Affiliation:

1. Auckland Cancer Society Research Centre, Faculty of Medical and Health Sciences, The University of Auckland, Private Bag 92019, Auckland, New Zealand, and Department of Radiation Oncology, Stanford University School of Medicine, Stanford, California 94305-5152

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm030399c

Reference67 articles.

1. SR 4233 (Tirapazamine): a new anticancer drug exploiting hypoxia in solid tumours

2. Tirapazamine: a bioreductive anticancer drug that exploits tumour hypoxia

3. Pretreatment oxygenation predicts radiation response in advanced squamous cell carcinoma of the head and neck

4. Tumor hypoxia adversely affects the prognosis of carcinoma of the head and neck

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