In Silico Identification and Biological Evaluation of Novel Selective Serum/Glucocorticoid-Inducible Kinase 1 Inhibitors Based on the Pyrazolo-Pyrimidine Scaffold-Reference-Cited by-同舟云学术

In Silico Identification and Biological Evaluation of Novel Selective Serum/Glucocorticoid-Inducible Kinase 1 Inhibitors Based on the Pyrazolo-Pyrimidine Scaffold

Published:2014-06-13 Issue:7 Volume:54 Page:1828-1832
ISSN:1549-9596
Container-title:Journal of Chemical Information and Modeling
language:en
Short-container-title:J. Chem. Inf. Model.

Author:

Ortuso Francesco,Amato Rosario,Artese Anna,D’antona Lucia,Costa Giosuè,Talarico Cristina,Gigliotti Francesco,Bianco Cataldo,Trapasso Francesco,Schenone Silvia¹,Musumeci Francesca¹,Botta Lorenzo²,Perrotti Nicola,Alcaro Stefano

Affiliation:

1. Department of “Farmacia”, University of Genoa, Viale Benedetto XV, 16132 Genova, Italy

2. Department of “Biotecnologie, Chimica e Farmacia”, University of Siena, Via A. Moro, 53100 Siena, Italy

Publisher

American Chemical Society (ACS)

Subject

Library and Information Sciences,Computer Science Applications,General Chemical Engineering,General Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/ci500235f

Reference37 articles.

1. Activation of Serum- and Glucocorticoid-induced Protein Kinase (Sgk) by Cyclic AMP and Insulin

2. sgk: an essential convergence point for peptide and steroid hormone regulation of ENaC-mediated Na+transport

3. mTOR-Raptor Binds and Activates SGK1 to Regulate p27 Phosphorylation

4. Identification of CISK, a new member of the SGK kinase family that promotes IL-3-dependent survival

5. Expression of the Serum- and Glucocorticoid-inducible Protein Kinase, Sgk, Is a Cell Survival Response to Multiple Types of Environmental Stress Stimuli in Mammary Epithelial Cells

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