Identification of a new structural family of SGK1 inhibitors as potential neuroprotective agents
Author:
Affiliation:
1. Centro de Investigaciones, Biológicas Margarita Salas-CSIC, Madrid, Spain
2. Centro de Investigación Biomédica en Red en Enfermedades Neurodegenerativas (CIBERNED), Instituto de Salud Carlos III, Madrid, Spain
Publisher
Informa UK Limited
Subject
Drug Discovery,Pharmacology,General Medicine
Link
https://www.tandfonline.com/doi/pdf/10.1080/14756366.2022.2153841
Reference40 articles.
1. The physiological impact of the serum and glucocorticoid-inducible kinase SGK1
2. Serum- and glucocorticoid-inducible kinase 1 and the response to cell stress
3. The N-terminus of the serum- and glucocorticoid-inducible kinase Sgk1 specifies mitochondrial localization and rapid turnover
4. Crystal structure of the kinase domain of serum and glucocorticoid-regulated kinase 1 in complex with AMP-PNP
5. Design and synthesis of orally bioavailable serum and glucocorticoid-regulated kinase 1 (SGK1) inhibitors
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