A novel trifluoromethyl quinoline derivative targeting SGK1 inducing autophagy and apoptosis via regulating mTOR/FOXO3a pathway in glioblastoma

Author:

Xiong Yu-feng,Li Cheng,Yu Jia,Chen Xiaozhong,Cheng Sha,Liu Xin-yu,Xu Bi-xue,Hu Xiao,Xu Guang-can,Luo Heng

Publisher

Elsevier BV

Reference43 articles.

1. The small molecule SI113 synergizes with mitotic spindle poisons in arresting the growth of human glioblastoma multiforme;Abbruzzese;Oncotarget,2017

2. AGC protein kinases: from structural mechanism of regulation to allosteric drug development for the treatment of human diseases;Arencibia;BBA,2013

3. Quinolone antibiotics;Blaskovich;Medchemcomm,2019

4. MGMT status as a clinical biomarker in glioblastoma;Butler;Trends Cancer.,2020

5. SGK1 in cancer: biomarker and drug target;Cicenas;Cancers (basel).,2022

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