Gram-Scale Synthesis of (+)-Discodermolide-Reference-Cited by-同舟云学术

Gram-Scale Synthesis of (+)-Discodermolide

Published:1999-10-29 Issue:11 Volume:1 Page:1823-1826
ISSN:1523-7060
Container-title:Organic Letters
language:en
Short-container-title:Org. Lett.

Author:

Smith Amos B.¹,Kaufman Michael D.¹,Beauchamp Thomas J.¹,LaMarche Matthew J.¹,Arimoto Hirokazu¹

Affiliation:

1. Department of Chemistry, Monell Chemical Senses Center, and Laboratory for Research on the Structure of Matter, University of Pennsylvania, Pennsylvania 19104

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/ol9910870

Reference20 articles.

1. Discodermolide: a new bioactive polyhydroxylated lactone from the marine sponge Discodermia dissoluta

2. (+)-Discodermolide binds to microtubules in stoichiometric ratio to tubulin dimers, blocks taxol binding and results in mitotic arrest

3. Discodermolide, A Cytotoxic Marine Agent That Stabilizes Microtubules More Potently Than Taxol,

4. Promotion of microtubule assembly in vitro by taxol

5. The Microtubule-Stabilizing Agent Discodermolide Competitively Inhibits the Binding of Paclitaxel (Taxol) to Tubulin Polymers, Enhances Tubulin Nucleation Reactions More Potently than Paclitaxel, and Inhibits the Growth of Paclitaxel-Resistant Cells

Cited by 151 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Challenges and Opportunities in Marine Ecological System and Drug Discovery;Marine Ecology: Current and Future Developments;2023-11-02

2. The sustainability impact of Nobel Prize Chemistry: life cycle assessment of C–C cross-coupling reactions;Green Chemistry;2023

3. Biosynthesis of Bioactive Natural Products Derived from Theonellidae Family Marine Sponges;Chemical and Pharmaceutical Bulletin;2023-01-01

4. Alkene Cross‐Metathesis Reactions;Organic Reactions;2021-06-15

5. Synthesis of C9‐C13 and C15‐C21 Subunits of Discodermolide;Asian Journal of Organic Chemistry;2020-06-30