Discodermolide, A Cytotoxic Marine Agent That Stabilizes Microtubules More Potently Than Taxol,

Author:

ter Haar Ernst1,Kowalski Richard J.1,Hamel Ernest1,Lin Chii M.1,Longley Ross E.1,Gunasekera Sarath P.1,Rosenkranz Herbert S.1,Day Billy W.1

Affiliation:

1. Department of Environmental and Occupational Health, Department of Pharmaceutical Sciences, and the University of Pittsburgh Cancer Institute, University of Pittsburgh, Pittsburgh, Pennsylvania 15238, Laboratory of Molecular Pharmacology, Developmental Therapeutics Program, Division of Cancer Treatment, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, and Division of Biomedical Marine Research, Harbor Branch Oceanographic Institution, Inc., Fort Pierce, Florida 34946

Publisher

American Chemical Society (ACS)

Subject

Biochemistry

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