(+)-Discodermolide binds to microtubules in stoichiometric ratio to tubulin dimers, blocks taxol binding and results in mitotic arrest-Reference-Cited by-同舟云学术

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(+)-Discodermolide binds to microtubules in stoichiometric ratio to tubulin dimers, blocks taxol binding and results in mitotic arrest

Published:1996-04 Issue:4 Volume:3 Page:287-293
ISSN:1074-5521
Container-title:Chemistry & Biology
language:en
Short-container-title:Chemistry & Biology

Author:

Hung Deborah T.,Chen Jie,Schreiber Stuart L.

Publisher

Elsevier BV

Subject

Clinical Biochemistry,Drug Discovery,Pharmacology,Molecular Biology,Molecular Medicine,General Medicine,Biochemistry

Reference21 articles.

1. Discodermolide — a new, marine-derived immunosuppressive compound. I. In vitro studies;Longley;Transplantation,1991

2. Discodermolide - a new, marine-derived immunosuppressive compound. II. In vivo studies;Longley;Transplantation,1991

3. Distinct binding and cellular properties of synthetic (+)- and (-)- discodermolides;Hung;Chemistry & Biology,1994

4. Immunosuppression by discodermolide;Longley;Ann. NY Acad. Sci.,1993

5. Total synthesis of the immunosuppressive agent (-)-discodermolide;Nerenberg;J. Am. Chem. Soc.,1993

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