Computer Simulations Reveal a Novel Nucleotide-Type Binding Orientation for Ellipticine-Based Anticancer c-kit Kinase Inhibitors
Author:
Affiliation:
1. Tyndall National Institute, Lee Maltings, Cork, Ireland, and Department of Chemistry and School of Pharmacy, Analytical and Biological Chemistry Research Facility, University College Cork, Western Road, Cork, Ireland
Publisher
American Chemical Society (ACS)
Subject
Biochemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/bi801239u
Reference68 articles.
1. Cell Signaling by Receptor Tyrosine Kinases
2. The biology of stem cell factor and its receptor C-kit
3. Early signaling pathways activated by c-Kit in hematopoietic cells
4. c-Kit—A hematopoietic cell essential receptor tyrosine kinase
5. Steel Factor and c-kit Protooncogene: Genetic Lessons in Signal Transduction
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