Evolution of a New Class of VEGFR-2 Inhibitors from Scaffold Morphing and Redesign-Reference-Cited by-同舟云学术

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Evolution of a New Class of VEGFR-2 Inhibitors from Scaffold Morphing and Redesign

Published:2016-02-08 Issue:4 Volume:7 Page:363-367
ISSN:1948-5875
Container-title:ACS Medicinal Chemistry Letters
language:en
Short-container-title:ACS Med. Chem. Lett.

Author:

Mainolfi Nello¹,Karki Rajeshri¹,Liu Fang²,Anderson Karen²

Affiliation:

1. Global Discovery Chemistry, Novartis Institutes for Biomedical Research, 100 Technology Square, Cambridge, Massachusetts 02139, United States

2. Ophthalmology, Novartis Institutes for Biomedical Research, 500 Technology Square, Cambridge, Massachusetts 02139, United States

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Drug Discovery,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acsmedchemlett.5b00486

Reference21 articles.

1. Ranibizumab versus Verteporfin for Neovascular Age-Related Macular Degeneration

2. Discovery of Oral VEGFR-2 Inhibitors with Prolonged Ocular Retention That Are Efficacious in Models of Wet Age-Related Macular Degeneration

3. The Biology of Vascular Endothelial Growth Factor

4. Vascular endothelial growth factor increases microvascular permeability via a Ca(2+)-dependent pathway

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3. Synthesis of novel 2‐acetamide‐5‐phenylthio‐1,3,4‐thiadiazole‐containing phenyl urea derivatives as potential VEGFR‐2 inhibitors;Archiv der Pharmazie;2022-01-10

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