Identification and SAR of Glycine Benzamides as Potent Agonists for the GPR139 Receptor-Reference-Cited by-同舟云学术

Identification and SAR of Glycine Benzamides as Potent Agonists for the GPR139 Receptor

Published:2015-07-28 Issue:9 Volume:6 Page:1015-1018
ISSN:1948-5875
Container-title:ACS Medicinal Chemistry Letters
language:en
Short-container-title:ACS Med. Chem. Lett.

Author:

Dvorak Curt A.¹,Coate Heather¹,Nepomuceno Diane¹,Wennerholm Michelle¹,Kuei Chester¹,Lord Brian¹,Woody David¹,Bonaventure Pascal¹,Liu Changlu¹,Lovenberg Timothy¹,Carruthers Nicholas I.¹

Affiliation:

1. Janssen Research & Development, LLC, San Diego, California 92121, United States

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Drug Discovery,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acsmedchemlett.5b00247

Reference11 articles.

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4. Aminopyrazole–Phenylalanine Based GPR142 Agonists: Discovery of Tool Compound and in Vivo Efficacy Studies

5. Dvorak, C. A.; Liu, C.; Kuei, C.Physiological ligands for GPR139 such asl-tryptophan,l-phenylalanine, or derivatives thereof and their therapeutic use. WO2014152917A2, 2014.

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