Pharmacological characterization of novel small molecule agonists and antagonists for the orphan receptor GPR139

Author:

Pallareti Lisa,Rath Tine F.,Trapkov Boris,Tsonkov Tsonko,Nielsen Anders Thorup,Harpsøe Kasper,Gentry Patrick R.,Bräuner-Osborne Hans,Gloriam David E.,Foster Simon R.ORCID

Funder

Lundbeckfonden

Danmarks Frie Forskningsfond

European Research Council

Publisher

Elsevier BV

Subject

Pharmacology

Reference42 articles.

1. Protection of primary dopaminergic midbrain neurons by GPR139 agonists supports different mechanisms of MPP(+) and rotenone toxicity;Bayer Andersen;Front. Cell. Neurosci.,2016

2. Canvas;Canvas,2017

3. Biased allosteric modulation at the CaS receptor engendered by structurally diverse calcimimetics;Cook;Br. J. Pharmacol.,2015

4. The Role of Orphan Receptor GPR139 in Neuropsychiatric Behavior. Neuropsychopharmacology;Dao,2021

5. Identification and SAR of Glycine benzamides as potent agonists for the GPR139 receptor;Dvorak;ACS Med. Chem. Lett.,2015

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