Novel N-Linked Isoquinoline Amides as LRRK2 Inhibitors for Treating Parkinson’s Disease
Author:
Affiliation:
1. Smith, Gambrell & Russell LLP, 1105 W. Peachtree Street NE, Suite 1000, Atlanta, Georgia 30309, United States
Publisher
American Chemical Society (ACS)
Subject
Organic Chemistry,Drug Discovery,Biochemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/acsmedchemlett.2c00263
Reference6 articles.
1. LRRK2 and idiopathic Parkinson’s disease
2. New therapeutic approaches to Parkinson's disease targeting GBA, LRRK2 and Parkin
3. Autophagy system as a potential therapeutic target for neurodegenerative diseases
4. Glucocerebrosidase 1 and leucine‐rich repeat kinase 2 in Parkinson disease and interplay between the two genes
5. LRRK2 recruitment, activity, and function in organelles
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