Successful Strategies for Mitigation of a Preclinical Signal for Phototoxicity in a DGAT1 Inhibitor-Reference-Cited by-同舟云学术

Successful Strategies for Mitigation of a Preclinical Signal for Phototoxicity in a DGAT1 Inhibitor

Published:2019-06-20 Issue:8 Volume:10 Page:1128-1133
ISSN:1948-5875
Container-title:ACS Medicinal Chemistry Letters
language:en
Short-container-title:ACS Med. Chem. Lett.

Author:

Harrison Tyler J.^ORCID,Bauer Daniel¹,Berdichevsky Alina,Chen Xin^ORCID,Duvadie Rohit,Hoogheem Benjamin,Hatsis Panos,Liu Qian,Mao Justin,Miduturu Vasumathy,Rocheford Erik,Zecri Frederic,Zessis Richard,Zheng Rui,Zhu Qingming,Streeper Ryan,Patel Sejal J.

Affiliation:

1. Preclinical Safety, Novartis Institutes for Biomedical Research, 4002 Basel, Switzerland

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Drug Discovery,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acsmedchemlett.9b00117

Reference33 articles.

1. THE FAMILIAL CHYLOMICRONEMIA SYNDROME

2. Chylomicronaemia—current diagnosis and future therapies

3. Identification of a gene encoding an acyl CoA:diacylglycerol acyltransferase, a key enzyme in triacylglycerol synthesis

4. Thematic Review Series: Glycerolipids. DGAT enzymes and triacylglycerol biosynthesis

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