Phototoxicity─Medicinal Chemistry Strategies for Risk Mitigation in Drug Discovery
Author:
Affiliation:
1. Global Discovery Chemistry, Novartis Institutes for Biomedical Research, 22 Windsor Street, Cambridge, Massachusetts 02139, United States
2. Preclinical Safety, Novartis Institutes for Biomedical Research, 4002 Basel, Switzerland
Publisher
American Chemical Society (ACS)
Subject
Drug Discovery,Molecular Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.3c00749
Reference79 articles.
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3. Drug and chemical induced photosensitivity from a clinical perspective
4. International Council for Harmonization (ICH). Non-clinical safety studies for the conduct of human clinical trials for pharmaceuticals (ICH M3 R2), 2009; https://www.ich.org/page/multidisciplinary-guidelines.
5. International Council for Harmonization (ICH). Photosafety evaluation of pharmaceuticals (ICH S10), 2013; https://www.ich.org/page/safety-guidelines.
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