Discovery of Zika Virus NS2B/NS3 Inhibitors That Prevent Mice from Life-Threatening Infection and Brain Damage-Reference-Cited by-同舟云学术

Discovery of Zika Virus NS2B/NS3 Inhibitors That Prevent Mice from Life-Threatening Infection and Brain Damage

Published:2020-01-15 Issue:10 Volume:11 Page:1869-1874
ISSN:1948-5875
Container-title:ACS Medicinal Chemistry Letters
language:en
Short-container-title:ACS Med. Chem. Lett.

Author:

Coluccia Antonio¹^ORCID,Puxeddu Michela¹,Nalli Marianna¹,Wei Chih-Ku²,Wu Yu-Hsuan³,Mastrangelo Eloise⁴⁵^ORCID,Elamin Tasneem⁵,Tarantino Delia⁴⁵,Bugert Joachim Jakob⁶,Schreiner Benno⁶,Nolte Juliane⁶,Schwarze Frank⁶,La Regina Giuseppe¹^ORCID,Lee Jin-Ching²⁷⁸⁹¹⁰,Silvestri Romano¹^ORCID

Affiliation:

1. Laboratory Affiliated to Institute Pasteur Italy − Cenci Bolognetti Foundation, Department of Drug Chemistry and Technologies, Sapienza University of Rome, Piazzale Aldo Moro 5, I-00185 Rome, Italy

2. Department of Biotechnology, College of Life Science, Kaohsiung Medical University, Kaohsiung, Taiwan

3. Institute of Basic Medical Sciences, College of Medicine, National Cheng Kung University, Tainan, Taiwan

4. Biophysics Institute, National Research Council, Via Celoria 26, I-20133 Milano, Italy

5. Department of Biosciences, Università di Milano, Via Celoria 26, I-20133 Milano, Italy

6. Bundeswehr Institute of Microbiology, Munich, Germany

7. PhD Program in Life Sciences, College of Life Science, Kaohsiung Medical University, Kaohsiung, Taiwan

8. Department of Medical Research, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan

9. Graduate Institute of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan

10. Drug Development and Value Creation Research Center, Kaohsiung Medical University, Kaohsiung, Taiwan

Funder

Ministero dell?Istruzione, dell?Universit? e della Ricerca

Kaohsiung Medical University

Ministry of Science and Technology, Taiwan

Istituto Pasteur Italia

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Drug Discovery,Biochemistry

Link

http://pubs.acs.org/doi/pdf/10.1021/acsmedchemlett.9b00405

Reference24 articles.

1. History, Epidemiology, and Clinical Manifestations of Zika: A Systematic Review

2. Dengue

3. Pathogenic flaviviruses

4. Fatal Sickle Cell Disease and Zika Virus Infection in Girl from Colombia

5. WHO. WHO statement on the first meeting of the International Health Regulations (2005) (IHR 2005) Emergency Committee on Zika virus and observed increase in neurological disorders and neonatal malformations. 1 February 2016 Statement. https://www.who.int. Accessed on 23-Nov-2019.

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