Integrated Platform for Expedited Synthesis–Purification–Testing of Small Molecule Libraries
Author:
Affiliation:
1. Discovery Chemistry and Technology, AbbVie Inc., 1 North Waukegan Road, North Chicago, Illinois 60064, United States
Funder
AbbVie
Publisher
American Chemical Society (ACS)
Subject
Organic Chemistry,Drug Discovery,Biochemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/acsmedchemlett.7b00054
Reference12 articles.
1. Accelerating Drug Discovery by Integrative Implementation of Laboratory Automation in the Work Flow
2. Rapid Discovery of a Novel Series of Abl Kinase Inhibitors by Application of an Integrated Microfluidic Synthesis and Screening Platform
3. Integrated Synthesis and Testing of Substituted Xanthine Based DPP4 Inhibitors: Application to Drug Discovery
4. Seamless Integration of Dose-Response Screening and Flow Chemistry: Efficient Generation of Structure-Activity Relationship Data of β-Secretase (BACE1) Inhibitors
5. An Integrated Synthesis–Purification System to Accelerate the Generation of Compounds in Pharmaceutical Discovery
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