Acyclic Nucleoside Phosphonates Containing a Second Phosphonate Group Are Potent Inhibitors of 6-Oxopurine Phosphoribosyltransferases and Have Antimalarial Activity-Reference-Cited by-同舟云学术

Acyclic Nucleoside Phosphonates Containing a Second Phosphonate Group Are Potent Inhibitors of 6-Oxopurine Phosphoribosyltransferases and Have Antimalarial Activity

Published:2013-03-19 Issue:6 Volume:56 Page:2513-2526
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Keough Dianne T.¹,Špaček Petr²,Hocková Dana²,Tichý Tomáš²,Vrbková Silvie²,Slavětínská Lenka²,Janeba Zlatko²,Naesens Lieve³,Edstein Michael D.⁴,Chavchich Marina⁴,Wang Tzu-Hsuan¹,de Jersey John¹,Guddat Luke W.¹

Affiliation:

1. The School of Chemistry and Molecular Biosciences, The University of Queensland, Brisbane 4072, Queensland, Australia

2. Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, v.v.i. Flemingovo nám. 2, CZ-166 10 Prague 6, Czech Republic

3. Rega Institute for Medical Research, Katholieke Universiteit Leuven, Minderbroedersstraat 10, B-3000 Leuven, Belgium

4. Australian Army Malaria Institute, Enoggera, Brisbane, Queensland 4051, Australia

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm301893b

Reference48 articles.

1. http://www.who.int/malaria/publications/atoz/9789241564106/en/index.html.

2. The global distribution of clinical episodes of Plasmodium falciparum malaria

3. The Threat of Artemisinin-Resistant Malaria