Studies Leading to Potent, Dual Inhibitors of Bcl-2 and Bcl-xL-Reference-Cited by-同舟云学术

Studies Leading to Potent, Dual Inhibitors of Bcl-2 and Bcl-xL

Published:2007-01-26 Issue:4 Volume:50 Page:641-662
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Bruncko Milan¹,Oost Thorsten K.¹,Belli Barbara A.¹,Ding Hong¹,Joseph Mary K.¹,Kunzer Aaron¹,Martineau Darlene¹,McClellan William J.¹,Mitten Michael¹,Ng Shi-Chung¹,Nimmer Paul M.¹,Oltersdorf Tilman¹,Park Cheol-Min¹,Petros Andrew M.¹,Shoemaker Alexander R.¹,Song Xiaohong¹,Wang Xilu¹,Wendt Michael D.¹,Zhang Haichao¹,Fesik Stephen W.¹,Rosenberg Saul H.¹,Elmore Steven W.¹

Affiliation:

1. Cancer Research, Global Pharmaceutical Research and Development, Abbott Laboratories, 100 Abbott Park Road, Abbott Park, Illinois 60064, and Idun Pharmaceuticals, 9380 Judicial Drive, San Diego, California 92121

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm061152t

Reference36 articles.

1. The Hallmarks of Cancer

2. The Bcl2 family: regulators of the cellular life-or-death switch

3. The Bcl-2 protein family: sensors and checkpoints for life-or-death decisions

4. How the Bcl-2 family of proteins interact to regulate apoptosis

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