Synthesis, Characterization, Mechanism of Decomposition, and Antiproliferative Activity of a Class of PEGylated Benzopolysulfanes Structurally Similar to the Natural Product Varacin-Reference-Cited by-同舟云学术

Synthesis, Characterization, Mechanism of Decomposition, and Antiproliferative Activity of a Class of PEGylated Benzopolysulfanes Structurally Similar to the Natural Product Varacin

Published:2010-07-26 Issue:16 Volume:75 Page:5549-5557
ISSN:0022-3263
Container-title:The Journal of Organic Chemistry
language:en
Short-container-title:J. Org. Chem.

Author:

Mahendran Adaickapillai¹,Vuong Angela¹,Aebisher David¹,Gong Yaqiong²,Bittman Robert²,Arthur Gilbert³,Kawamura Akira⁴,Greer Alexander¹

Affiliation:

1. Department of Chemistry, Brooklyn College of The City University of New York, Brooklyn, New York 11210

2. Department of Chemistry and Biochemistry, Queens College of The City University of New York, Flushing, New York 11367

3. Department of Biochemistry and Medical Genetics, University of Manitoba, Winnipeg, Manitoba, Canada R3E 0W3

4. Department of Chemistry, Hunter College of The City University of New York, New York, New York 10065

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/jo100870q

Reference35 articles.

1. Varacin: a novel benzopentathiepin from Lissoclinum vareau that is cytotoxic toward a human colon tumor

2. Lissoclibadins 1–3, three new polysulfur alkaloids, from the ascidian Lissoclinum cf. badium

3. Lissoclinotoxin A, an antibiotic 1,2,3-trithiane derivative from the tunicate Lissoclinum perforatum.

4. Pentathiepins and trithianes from two Lissoclinum species and a Eudistoma sp.: inhibitors of protein kinase C

5. Five new alkaloids from the tropical ascidian, Lissoclinum sp. lissoclinotoxin A is chiral

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