Rapid LC-MS Drug Metabolite Profiling Using Microsomal Enzyme Bioreactors in a Parallel Processing Format-Reference-Cited by-同舟云学术

Rapid LC-MS Drug Metabolite Profiling Using Microsomal Enzyme Bioreactors in a Parallel Processing Format

Published:2009-11-11 Issue:24 Volume:81 Page:9921-9929
ISSN:0003-2700
Container-title:Analytical Chemistry
language:en
Short-container-title:Anal. Chem.

Author:

Bajrami Besnik¹,Zhao Linlin¹,Schenkman John B.¹,Rusling James F.¹

Affiliation:

1. Department of Chemistry, University of Connecticut, Storrs, Connecticut 06269-3060, and Department of Cell Biology, University of Connecticut Health Center, Farmington, Connecticut 06032, and School of Chemistry, National Univ. of Ireland at Galway, Ireland

Publisher

American Chemical Society (ACS)

Subject

Analytical Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/ac9015853

Reference40 articles.

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3. DRUG-DRUG INTERACTIONS FOR UDP-GLUCURONOSYLTRANSFERASE SUBSTRATES: A PHARMACOKINETIC EXPLANATION FOR TYPICALLY OBSERVED LOW EXPOSURE (AUCI/AUC) RATIOS

4. Extrapolation of Diclofenac Clearance from in Vitro Microsomal Metabolism Data: Role of Acyl Glucuronidation and Sequential Oxidative Metabolism of the Acyl Glucuronide

5. Bioanalysis without Sample Cleanup or Chromatography: The Evaluation and Initial Implementation of Direct Analysis in Real Time Ionization Mass Spectrometry for the Quantification of Drugs in Biological Matrixes

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