Bioanalysis without Sample Cleanup or Chromatography: The Evaluation and Initial Implementation of Direct Analysis in Real Time Ionization Mass Spectrometry for the Quantification of Drugs in Biological Matrixes
Author:
Affiliation:
1. Department of Drug Metabolism and Pharmacokinetics, Millennium Pharmaceuticals, Inc., Cambridge, Massachusetts 02139, and IonSense, Inc., Saugus, Massachusetts 01906
Publisher
American Chemical Society (ACS)
Subject
Analytical Chemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/ac801734t
Reference19 articles.
1. Strategy of Utilizing In Vitro and In Vivo ADME Tools for Lead Optimization and Drug Candidate Selection
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5. High-speed liquid chromatography/tandem mass spectrometry using a monolithic column for high-throughput bioanalysis
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