14-Azacamptothecin: A Potent Water-Soluble Topoisomerase I Poison
Author:
Affiliation:
1. Departments of Chemistry and Biology, University of Virginia, Charlottesville, Virginia 22904
Publisher
American Chemical Society (ACS)
Subject
Colloid and Surface Chemistry,Biochemistry,General Chemistry,Catalysis
Link
https://pubs.acs.org/doi/pdf/10.1021/ja0442769
Reference23 articles.
1. Plant Antitumor Agents. I. The Isolation and Structure of Camptothecin, a Novel Alkaloidal Leukemia and Tumor Inhibitor from Camptotheca acuminata1,2
2. Camptothecin induces protein-linked DNA breaks via mammalian DNA topoisomerase I.
3. Molecular and Biological Determinants of the Cytotoxic Actions of Camptothecins: Perspective for the Development of New Topoisomerase I Inhibitors
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