Molecular and Biological Determinants of the Cytotoxic Actions of Camptothecins: Perspective for the Development of New Topoisomerase I Inhibitors

Author:

KOHN KURT W.,POMMIER YVES

Publisher

Wiley

Subject

History and Philosophy of Science,General Biochemistry, Genetics and Molecular Biology,General Neuroscience

Reference57 articles.

1. Camptothecin;Wall;Ann. N.Y. Acad. Sci.,1996

2. Camptothecin and taxol: discovery to clinic;Wall;Thirteenth Bruce F. Cain Memorial Award Lecture. Cancer Res.,1995

3. Camptothecin and taxol: discovery to clinic;Wall;Medicinal Res. Rev.,1998

4. Plant antitumor agents. I. The isolation and structure of camptothecin, a novel alkaloidal leukemia and tumor inhibitor from Camptotheca accuminata;Wall;J. Am. Chem Soc.,1966

5. Camptothecin induces protein-linked DNA breaks via mammalian DNA topoisomerase I;Hsiang;J. Biol. Chem.,1985

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