Detection and Quantitation of IgG 1 Hinge Aspartate Isomerization: A Rapid Degradation in Stressed Stability Studies
Author:
Affiliation:
1. Department of Analytical and Formulation Sciences, Amgen Inc.,1201 Amgen Court W, Seattle, Washington 98119
Publisher
American Chemical Society (ACS)
Subject
Analytical Chemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/ac901258g
Reference42 articles.
1. Small molecules for small minds? The case for biologic pharmaceuticals
2. Monoclonal Antibody "Gold Rush"
3. Monoclonal antibodies come of age
4. Recombinant therapeutic monoclonal antibodies: Mechanisms of action in relation to structural and functional duality
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