Identification and characterization of an unexpected isomerization motif in CDRH2 that affects antibody activity-Reference-Cited by-同舟云学术

登录注册会员服务联系我们

Identification and characterization of an unexpected isomerization motif in CDRH2 that affects antibody activity

Published:2023-05-25 Issue:1 Volume:15 Page:
ISSN:1942-0862
Container-title:mAbs
language:en
Short-container-title:mAbs

Author:

Yi Meiqi¹,Sun Jian¹,Sun Hanzi²,Wang Yifei¹,Hou Shan¹,Jiang Beibei³,Xie Yuanyuan¹,Ji Ruyue¹,Xue Liu¹,Ding Xiao⁴,Song Xiaomin³,Xu April¹,Huang Chichi¹,Quan Quan¹,Song Jing¹

Affiliation:

1. Department of Biologics, BeiGene (Beijing) Co. Ltd, Beijing, China

2. Department of Molecular Science, BeiGene (Beijing) Co. Ltd, Beijing, China

3. Department of Pharmacology, BeiGene (Beijing) Co. Ltd, Beijing, China

4. Department of Translational Science, BeiGene (Beijing) Co. Ltd, Beijing, China

Funder

there is no funding

Publisher

Informa UK Limited

Subject

Immunology,Immunology and Allergy

Link

https://www.tandfonline.com/doi/pdf/10.1080/19420862.2023.2215364

Reference33 articles.

1. Recombinant Antibodies as Therapeutic Agents

2. Monoclonal antibody successes in the clinic

3. Therapeutic antibodies: successes, limitations and hopes for the future

4. Effect of Trastuzumab–HER2 Complex Formation on Stress-Induced Modifications in the CDRs of Trastuzumab

5. Isomerization of an Aspartic Acid Residue in the Complementarity-Determining Regions of a Recombinant Antibody to Human IgE: Identification and Effect on Binding Affinity

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线，采集、加工和组织学术论文而形成的新型学术文献查询和分析系统，可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容，当前同舟云学术共收录了国内外主流学术期刊6万余种，收集的期刊论文及会议论文总量共计约1.5亿篇，并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询！咨询电话：010-8811{复制后删除}0370

www.globalauthorid.com

TOP