Ajoene Is an Inhibitor and Subversive Substrate of Human Glutathione Reductase and Trypanosoma cruzi Trypanothione Reductase: Crystallographic, Kinetic, and Spectroscopic Studies-Reference-Cited by-同舟云学术

Ajoene Is an Inhibitor and Subversive Substrate of Human Glutathione Reductase and Trypanosoma cruzi Trypanothione Reductase: Crystallographic, Kinetic, and Spectroscopic Studies

Published:1999-01-21 Issue:3 Volume:42 Page:364-372
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Gallwitz Helge¹,Bonse Susanne¹,Martinez-Cruz Alfonso¹,Schlichting Ilme¹,Schumacher Karin¹,Krauth-Siegel R. Luise¹

Affiliation:

1. Biochemie-Zentrum, Heidelberg University, Im Neuenheimer Feld 328, D-69120 Heidelberg, Germany, Abteilung Biophysik, Max-Planck-Institut für Medizinische Forschung, Jahnstrasse 29, D-69120 Heidelberg, Germany, Max-Planck-Institut für Molekulare Physiologie, Rheinlanddamm 201, D-44139 Dortmund, Germany, and Gesellschaft für Biotechnologische Forschung, Mascheroder Weg 1, D-38124 Braunschweig, Germany

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm980471k

Reference45 articles.

1. The Organosulfur Chemistry of the GenusAllium - Implications for the Organic Chemistry of Sulfur

2. Ajoene, the antiplatelet compound derived from garlic, specifically inhibits platelet release reaction by affecting the plasma membrane internal microviscosity

3. The cytotoxic effect of ajoene, a natural product from garlic, investigated with different cell lines

4. Inhibition of phosphatidylcholine biosynthesis and cell proliferation in trypanosomacruzi by ajoene, an antiplatelet compound isolated from garlic

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