Inhibition of phosphatidylcholine biosynthesis and cell proliferation in trypanosomacruzi by ajoene, an antiplatelet compound isolated from garlic

Author:

Urbina Julio A.,Marchan Edgar,Lazardi Keyla,Visbal Gonzalo,Apitz-Castro Rafael,Gil Francisco,Aguirre Tania,Piras Marta M.,Piras Romano

Publisher

Elsevier BV

Subject

Pharmacology,Biochemistry

Reference39 articles.

1. Effect of garlic extract and of three pure components isolated from it on human platelet aggregation, arachidonate metabolism, release reaction and platelet ultrastructure;Apitz-Castro;Throm Res,1983

2. Reversible prevention of platelet activation by (E,Z)-4,5,9-trithiadodeca-1,6,11-triene-9-oxide (ajoene) in dogs under extracorporeal circulation;Apitz-Castro;Arzneimittelforschung,1988

3. Antithrombic organosulfur compounds from garlic: Structural, mechanistic and synthetic studies;Block;J Am Chem Soc,1986

4. The molecular basis of the antiplatelet action of ajoene: Direct interaction with the fibrinogen receptor;Apitz-Castro;Biochem Biophys Res Commun,1986

5. Garlic: Molecular basis of the putative ‘vampire-repellant’ action and other matters related to heart and blood;Jain;Trends Biochem Sci,1987

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