Water-Compatible Cycloadditions of Oligonucleotide-Conjugated Strained Allenes for DNA-Encoded Library Synthesis-Reference-Cited by-同舟云学术

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Water-Compatible Cycloadditions of Oligonucleotide-Conjugated Strained Allenes for DNA-Encoded Library Synthesis

Published:2020-04-08 Issue:17 Volume:142 Page:7776-7782
ISSN:0002-7863
Container-title:Journal of the American Chemical Society
language:en
Short-container-title:J. Am. Chem. Soc.

Author:

Westphal Matthias V.¹²,Hudson Liam¹²,Mason Jeremy W.¹²,Pradeilles Johan A.¹²,Zécri Frédéric J.²,Briner Karin²,Schreiber Stuart L.¹³^ORCID

Affiliation:

1. Chemical Biology and Therapeutics Science Program, Broad Institute, 415 Main Street, Cambridge, Massachusetts 02142, United States

2. Novartis Institutes for BioMedical Research, 181 Massachusetts Avenue, Cambridge, Massachusetts 02139, United States

3. Department of Chemistry and Chemical Biology, Harvard University, 12 Oxford Street, Cambridge, Massachusetts 02138, United States

Funder

National Institute of General Medical Sciences

Publisher

American Chemical Society (ACS)

Subject

Colloid and Surface Chemistry,Biochemistry,General Chemistry,Catalysis

Link

https://pubs.acs.org/doi/pdf/10.1021/jacs.9b13186

Reference48 articles.

1. DNA-Encoded Chemical Libraries: A Selection System Based on Endowing Organic Compounds with Amplifiable Information

2. What Do You Get from DNA-Encoded Libraries?

3. Activity-Based DNA-Encoded Library Screening

4. An Integrated Microfluidic Processor for DNA-Encoded Combinatorial Library Functional Screening

5. Diversity-oriented synthesis as a tool for the discovery of novel biologically active small molecules

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