What Do You Get from DNA-Encoded Libraries?
Author:
Affiliation:
1. Roche Pharma Research and Early Development (pRED), Roche Innovation Center Basel, F. Hoffmann-La Roche Ltd, Grenzacherstrasse 124, CH-4070 Basel, Switzerland
Publisher
American Chemical Society (ACS)
Subject
Organic Chemistry,Drug Discovery,Biochemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/acsmedchemlett.8b00128
Reference16 articles.
1. DNA-encoded chemistry: enabling the deeper sampling of chemical space
2. Discovery of a First-in-Class Receptor Interacting Protein 1 (RIP1) Kinase Specific Clinical Candidate (GSK2982772) for the Treatment of Inflammatory Diseases
3. Discovering Drugs with DNA-Encoded Library Technology: From Concept to Clinic with an Inhibitor of Soluble Epoxide Hydrolase
4. Design, synthesis and selection of DNA-encoded small-molecule libraries
5. Analysis of the productivity of DNA encoded libraries
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