Intramolecular H-Bonds in an Organocatalyst Enabled an Asymmetric Michael/Alkylation Cascade Reaction to Construct Spirooxindoles Incorporating a Densely Substituted Cyclopropane Motif-Reference-Cited by-同舟云学术

Intramolecular H-Bonds in an Organocatalyst Enabled an Asymmetric Michael/Alkylation Cascade Reaction to Construct Spirooxindoles Incorporating a Densely Substituted Cyclopropane Motif

Published:2022-11-15 Issue:46 Volume:24 Page:8553-8558
ISSN:1523-7060
Container-title:Organic Letters
language:en
Short-container-title:Org. Lett.

Author:

Wang Na¹^ORCID,Yan Xiao¹,Hu Zi-Tian¹,Feng Yi¹,Zhu Lei¹^ORCID,Chen Zi-Hang¹,Wang Huan¹,Wang Quan-Ling¹,Ouyang Qin¹,Zheng Peng-Fei¹^ORCID

Affiliation:

1. College of Pharmacy, Third Military Medical University, Chongqing, 400038, China

Funder

Chongqing Municipal Education Commission

Natural Science Foundation of Chongqing

Third Military Medical University

China Postdoctoral Science Foundation

Ministry of Human Resources and Social Security

National Natural Science Foundation of China

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.orglett.2c03578

Reference49 articles.

1. Stereoselective Cyclopropanation Reactions

2. Biosynthesis and Metabolism of Cyclopropane Rings in Natural Compounds

3. Put a ring on it: application of small aliphatic rings in medicinal chemistry

4. Cyclopropanes in organocatalytic transformations

5. Escape from Flatland: Increasing Saturation as an Approach to Improving Clinical Success

Cited by 9 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Betaketothioesters in Organocatalysis: Harnessing Nucleophilic Reactivity, the Fluorophobic Effect, and Expanding the Substrate Repertoire;Tetrahedron Chem;2024-09

2. Organocatalytic Enantioselective Synthesis of Nitrocyclopropanes Bearing a Thioester Group and Three Stereogenic Centers;Advanced Synthesis & Catalysis;2024-05-23

3. Reversal of enantioselectivity in cobalt(ii)-catalyzed asymmetric Michael–alkylation reactions: synthesis of spiro-cyclopropane-oxindoles;Organic Chemistry Frontiers;2024

4. Unveiling the beauty of cyclopropane formation: a comprehensive survey of enantioselective Michael initiated ring closure (MIRC) reactions;Organic Chemistry Frontiers;2024

5. Palladium/copper-cocatalyzed three-component tandem cyclization of o-alkenyl arylisocyanides and sulfur ylides with alcohols: direct synthesis of spiro 3,3′-cyclopropyl oxindoles;Organic Chemistry Frontiers;2024