A Reversible and Highly Selective Inhibitor of the Proteasomal Ubiquitin Receptor Rpn13 Is Toxic to Multiple Myeloma Cells
Author:
Affiliation:
1. Departments of Chemistry and Cancer Biology, The Scripps Research Institute, 130 Scripps Way, Jupiter, Florida 33458, United States
Funder
National Heart, Lung, and Blood Institute
National Cancer Institute
Publisher
American Chemical Society (ACS)
Subject
Colloid and Surface Chemistry,Biochemistry,General Chemistry,Catalysis
Link
https://pubs.acs.org/doi/pdf/10.1021/jacs.5b02069
Reference47 articles.
1. The Proteasome: Paradigm of a Self-Compartmentalizing Protease
2. The Regulatory Particle of the Saccharomyces cerevisiae Proteasome
3. The proteasome under the microscope: the regulatory particle in focus
4. Structure of 20S proteasome from yeast at 2.4Å resolution
5. Crystal Structure of Epoxomicin:20S Proteasome Reveals a Molecular Basis for Selectivity of α‘,β‘-Epoxyketone Proteasome Inhibitors
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