Identification of the Key Residue of Calcitonin Gene Related Peptide (CGRP) 27−37 to Obtain Antagonists with Picomolar Affinity at the CGRP Receptor-Reference-Cited by-同舟云学术

Identification of the Key Residue of Calcitonin Gene Related Peptide (CGRP) 27−37 to Obtain Antagonists with Picomolar Affinity at the CGRP Receptor

Published:2005-12-22 Issue:2 Volume:49 Page:616-624
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Lang Manja¹,De Pol Silvia¹,Baldauf Carsten¹,Hofmann Hans-Jörg¹,Reiser Oliver¹,Beck-Sickinger Annette G.¹

Affiliation:

1. Institute of Biochemistry, University of Leipzig, D-04103 Leipzig, Germany, and Institute of Organic Chemistry, University of Regensburg, D-93040 Regensburg, Germany

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm050613s

Reference48 articles.

1. Biological properties of two models of calcitonin gene related peptide with idealized amphiphilic .alpha.-helices of different lengths

2. Solution structure of human calcitonin gene-related peptide by proton NMR and distance geometry with restrained molecular dynamics

3. Isolation and characterization of human calcitonin gene-related peptide

4. Expression in Brain of a Messenger RNA Encoding a Novel Neuropeptide Homologous to Calcitonin Gene-Related Peptide

5. International Union of Pharmacology. XXXII. The Mammalian Calcitonin Gene-Related Peptides, Adrenomedullin, Amylin, and Calcitonin Receptors

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