Lamivudine as a Nucleoside Template To Engineer DNA-Like Double-Stranded Helices in Crystals-Reference-Cited by-同舟云学术

Lamivudine as a Nucleoside Template To Engineer DNA-Like Double-Stranded Helices in Crystals

Published:2014-08-04 Issue:9 Volume:14 Page:4691-4702
ISSN:1528-7483
Container-title:Crystal Growth & Design
language:en
Short-container-title:Crystal Growth & Design

Author:

Vasconcelos Alline Torquato¹,da Silva Cameron Capeletti¹,Queiroz Júnior Luiz Henrique Keng¹,Santana Mábio João¹,Ferreira Vinicius Sousa¹,Martins Felipe Terra¹

Affiliation:

1. Instituto de Química, Universidade Federal de Goiás, Campus Samambaia, CP 131, Goiânia, Goiás 74001-970, Brazil

Funder

Conselho Nacional de Desenvolvimento Científico e Tecnológico

Publisher

American Chemical Society (ACS)

Subject

Condensed Matter Physics,General Materials Science,General Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/cg500786m

Reference36 articles.

1. (-)-2'-deoxy-3'-thiacytidine is a potent, highly selective inhibitor of human immunodeficiency virus type 1 and type 2 replication in vitro

2. L- and D-Enantiomers of 2′,3′-Dideoxycytidine 5′-Triphosphate Analogs as Substrates for Human DNA Polymerases

3. Deoxycytidine deaminase-resistant stereoisomer is the active form of (+/-)-2',3'-dideoxy-3'-thiacytidine in the inhibition of hepatitis B virus replication.

4. Mechanistic studies show that (−)‐FTC‐TP is a better inhibitor of HIV‐1 reverse transcriptase than 3TC‐TP

5. Lamivudine (3TC) resistance in HIV-1 reverse transcriptase involves steric hindrance with beta -branched amino acids

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