Mechanistic studies show that (−)‐FTC‐TP is a better inhibitor of HIV‐1 reverse transcriptase than 3TC‐TP-Reference-Cited by-同舟云学术

Mechanistic studies show that (−)‐FTC‐TP is a better inhibitor of HIV‐1 reverse transcriptase than 3TC‐TP

Published:1999-09 Issue:12 Volume:13 Page:1511-1517
ISSN:0892-6638
Container-title:The FASEB Journal
language:en
Short-container-title:FASEB j.

Author:

Feng Joy Y.¹,Shi Junxing²,Schinazi Raymond F.²,Anderson Karen S.¹

Affiliation:

1. Department of PharmacologyYale University School of Medicine New Haven Connecticut 06520‐8066 USA

2. Laboratory of Biochemical PharmacologyDepartment of PediatricsEmory University School of Medicine/VAMC Decatur Georgia 30033 USA

Funder

National Institutes of Health

U.S. Department of Veterans Affairs

Publisher

Wiley

Subject

Genetics,Molecular Biology,Biochemistry,Biotechnology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1096/fasebj.13.12.1511

Reference32 articles.

1. In search of a selective antiviral chemotherapy

2. Activities of the four optical isomers of 2',3'-dideoxy-3'-thiacytidine (BCH-189) against human immunodeficiency virus type 1 in human lymphocytes

3. Deoxycytidine deaminase‐resistant stereoisomer is the active form of (±)‐2′,3′‐dideoxy‐3′‐thiacytidine in the inhibition of hepatitis B virus replication;Chang C.‐N.;J. Biol. Chem.,1992

4. (-)-2'-deoxy-3'-thiacytidine is a potent, highly selective inhibitor of human immunodeficiency virus type 1 and type 2 replication in vitro

5. Selective inhibition of human immunodeficiency viruses by racemates and enantiomers of cis-5-fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]cytosine

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