Iron-Catalyzed Synthesis of Conformationally Restricted Bicyclic N-Heterocycles via [2+2]-Cycloaddition: Exploring Ring Expansion─Mechanistic Insights and Challenges
Author:
Affiliation:
1. Anorganisch-Chemisches Institut, Universität Heidelberg, Im Neuenheimer Feld 276, Heidelberg 69120, Germany
2. Institut für Anorganische Chemie, Georg-August-Universität, Göttingen, Tammannstraße 4, Göttingen 37077, Germany
Funder
Deutsche Forschungsgemeinschaft
Fonds der Chemischen Industrie
Publisher
American Chemical Society (ACS)
Subject
Catalysis,General Chemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/acscatal.3c01305
Reference59 articles.
1. Escape from Flatland: Increasing Saturation as an Approach to Improving Clinical Success
2. Conformational Restriction and Steric Hindrance in Medicinal Chemistry
3. Mitigating Heterocycle Metabolism in Drug Discovery
4. The impact of aromatic ring count on compound developability – are too many aromatic rings a liability in drug design?
5. An oral SARS-CoV-2 M pro inhibitor clinical candidate for the treatment of COVID-19
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