Bacterial Lactonases ZenA with Noncanonical Structural Features Hydrolyze the Mycotoxin Zearalenone

Author:

Fruhauf Sebastian1,Pühringer Dominic2,Thamhesl Michaela1,Fajtl Patricia1,Kunz-Vekiru Elisavet3,Höbartner-Gussl Andreas1,Schatzmayr Gerd1,Adam Gerhard4,Damborsky Jiri56ORCID,Djinovic-Carugo Kristina278ORCID,Prokop Zbynek56ORCID,Moll Wulf-Dieter1ORCID

Affiliation:

1. dsm-firmenich Animal Nutrition and Health R&D Center Tulln, Technopark 1, Tulln 3430, Austria

2. Department for Structural and Computational Biology, Max Perutz Laboratories, University of Vienna, Campus Vienna Biocenter 5, Vienna 1030, Austria

3. Institute of Bioanalytics and Agro-Metabolomics, Department of Agrobiotechnology IFA-Tulln, University of Natural Resources and Life Sciences Vienna (BOKU), Konrad-Lorenz-Straße 20, Tulln 3430, Austria

4. Institute of Microbial Genetics, Department of Applied Genetics and Cell Biology, University of Natural Resources and Life Sciences Vienna (BOKU), Konrad-Lorenz-Straße 24, Tulln 3430, Austria

5. Loschmidt Laboratories, Department of Experimental Biology and RECETOX, Faculty of Science, Masaryk University, Kamenice 5, Bld. A13, Brno 625 00, Czech Republic

6. International Clinical Research Center, St. Anne’s University Hospital Brno, Pekarska 53, Brno 656 91, Czech Republic

7. Department of Biochemistry, Faculty of Chemistry and Chemical Technology, University of Ljubljana, Ljubljana 1000, Slovenia

8. European Molecular Biology Laboratory (EMBL) Grenoble, Grenoble 38000, France

Funder

European Commission

??sterreichische Forschungsf??rderungsgesellschaft

Ministerstvo ??kolstv??, Ml??de??e a Telov??chovy

National Institute for Neurology Research

Publisher

American Chemical Society (ACS)

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