Structure-based Drug Discovery Using GPCR Homology Modeling: Successful Virtual Screening for Antagonists of the Alpha1A Adrenergic Receptor
Author:
Affiliation:
1. Aventis Pharma Deutschland GmBH, Ein Unternehmen der Sanofi-Aventis Gruppe, DI&A Chemistry, Computational Chemistry, Industriepark Höchst, Building G838, D-65926 Frankfurt am Main, Germany
Publisher
American Chemical Society (ACS)
Subject
Drug Discovery,Molecular Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/jm0491804
Reference72 articles.
1. α1-Adrenoceptor subtypes
2. Identification of Nonpeptidic Urotensin II Receptor Antagonists by Virtual Screening Based on a Pharmacophore Model Derived from Structure−Activity Relationships and Nuclear Magnetic Resonance Studies on Urotensin II
3. Lead Generation Using Pharmacophore Mapping and Three-Dimensional Database Searching: Application to Muscarinic M3 Receptor Antagonists
Cited by 236 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Computational Chemistry for the Identification of Lead Compounds for Radiotracer Development;Pharmaceuticals;2023-02-18
2. Virtual screening;Computational Approaches in Drug Discovery, Development and Systems Pharmacology;2023
3. Methodological Verification-based Screening of the Representative Ingredients for Traditional Chinese Medicine: Taking Astragalus as an Example for Interfering with Cervical Cancer;Current Computer-Aided Drug Design;2022-08
4. Computational modeling and druggability assessment of Aggregatibacter actinomycetemcomitans leukotoxin;Computer Methods and Programs in Biomedicine;2022-07
5. An Appraisal of Skill Gaps in Bioinformatics Education;Current Bioinformatics;2021-11
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3