7-Substituted 5-Amino-2-(2-furyl)pyrazolo[4,3-e]-1,2,4-triazolo[1,5-c]pyrimidines as A2A Adenosine Receptor Antagonists: A Study on the Importance of Modifications at the Side Chain on the Activity and Solubility-Reference-Cited by-同舟云学术

7-Substituted 5-Amino-2-(2-furyl)pyrazolo[4,3-e]-1,2,4-triazolo[1,5-c]pyrimidines as A2A Adenosine Receptor Antagonists: A Study on the Importance of Modifications at the Side Chain on the Activity and Solubility

Published:2001-12-06 Issue:1 Volume:45 Page:115-126
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Baraldi Pier Giovanni¹,Cacciari Barbara¹,Romagnoli Romeo¹,Spalluto Giampiero¹,Monopoli Angela¹,Ongini Ennio¹,Varani Katia¹,Borea Pier Andrea¹

Affiliation:

1. Dipartimento di Scienze Farmaceutiche, Università degli Studi di Ferrara, Via Fossato di Mortara 17/19, I-44100 Ferrara, Italy, Dipartimento di Scienze Farmaceutiche, Università degli Studi di Trieste, Piazzale Europa 1, I-34127 Trieste, Italy, Centro Ricerche Schering-Plough, Parco Scientifico S. Raffaele, Via Olgettina 58, I-20132 Milano, Italy, and Dipartimento di Medicina Clinica e Sperimentale-Sezione di Farmacologia, Università degli Studi di Ferrara, Via Fossato di Mortara 17/19, I-44100 Ferrara,...

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm010924c

Reference32 articles.

1. The role of receptor structure in determining adenosine receptor activity

2. Distribution, biochemistry and function of striatal adenosine A2A receptors

3. Pharmacology of adenosine A2A receptors

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