Synthesis of HCV Replicase Inhibitors: Base-Catalyzed Synthesis of Protected α-Hydrazino Esters and Selective Aerobic Oxidation with Catalytic Pt/Bi/C for Synthesis of Imidazole-4,5-dicarbaldehyde-Reference-Cited by-同舟云学术

Synthesis of HCV Replicase Inhibitors: Base-Catalyzed Synthesis of Protected α-Hydrazino Esters and Selective Aerobic Oxidation with Catalytic Pt/Bi/C for Synthesis of Imidazole-4,5-dicarbaldehyde

Published:2013-11-13 Issue:23 Volume:78 Page:11680-11690
ISSN:0022-3263
Container-title:The Journal of Organic Chemistry
language:en
Short-container-title:J. Org. Chem.

Author:

Bowman Roy K.¹,Brown Andrew D.¹,Cobb Jannine H.¹,Eaddy John F.¹,Hatcher Mark A.¹,Leivers Martin R.¹,Miller John F.¹,Mitchell Mark B.¹,Patterson Daniel E.¹,Toczko Matthew A.¹,Xie Shiping¹

Affiliation:

1. Product Development and ‡HCV Discovery Performance Unit, GlaxoSmithKline, 5 Moore Drive, Research Triangle Park, North Carolina 27709, United States

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/jo4014595

Reference26 articles.

1. World Health Organization (WHO). Hepatitis C Fact SheetNo. 164, updated July 2013: http://www.who.int/mediacentre/factsheets/fs164/en/index.html(accessed July 5, 2013) .

2. Treatment of chronic hepatitis C with PEGylated interferon and ribavirin

3. Current therapy and new molecular approaches to antiviral treatment and prevention of hepatitis C

4. Investigational drugs for hepatitis C

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