Synthesis and Structure–Activity Relationships of N-Methyl-5,6,7-trimethoxylindoles as Novel Antimitotic and Vascular Disrupting Agents-Reference-Cited by-同舟云学术

Synthesis and Structure–Activity Relationships of N-Methyl-5,6,7-trimethoxylindoles as Novel Antimitotic and Vascular Disrupting Agents

Published:2013-02-12 Issue:4 Volume:56 Page:1467-1477
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Zhao Deng-Gao¹,Chen JianJun¹,Du Ya-Rong¹,Ma Yan-Yan¹,Chen Ya-Xiong²,Gao Kun¹,Hu Bu-Rong²

Affiliation:

1. State Key Laboratory of Applied Organic Chemistry, College of Chemistry and Chemical Engineering, Lanzhou University, Lanzhou 730000, People’s Republic of China

2. Key Laboratory of Heavy Ion Radiation Biology and Medicine, Institute of Modern Physics, Chinese Academy of Sciences, Lanzhou 730000, People’s Republic of China

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm3014663

Reference32 articles.

1. Angiogenesis in cancer, vascular, rheumatoid and other disease

2. Vascular-targeting therapies for treatment of malignant disease

3. Disrupting tumour blood vessels

4. Inhibition of growth of colon 38 adenocarcinoma by vinblastine and colchicine: Evidence for a vascular mechanism

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