Preservation and stability of cell therapy products: recommendations from an expert workshop-Reference-Cited by-同舟云学术

Preservation and stability of cell therapy products: recommendations from an expert workshop

Published:2017-07 Issue:5 Volume:12 Page:553-564
ISSN:1746-0751
Container-title:Regenerative Medicine
language:en
Short-container-title:Regenerative Medicine

Author:

Stacey Glyn N¹,Connon Che J²,Coopman Karen³,Dickson Alan J⁴,Fuller Barry⁵,Hunt Charles J¹,Kemp Paul⁶,Kerby Julie⁷,Man Jennifer¹,Matejtschuk Paul⁸,Moore Harry⁹,Morris John¹⁰,Oreffo Richard OC¹¹,Slater Nigel¹²,Ward Stephen⁶,Wiggins Claire¹³,Zimmermann Heiko¹⁴¹⁵¹⁶

Affiliation:

1. UK Stem Cell Bank, Division of Advanced Therapies, NIBSC, South Mimms, Hertfordshire, UK

2. Institute of Genetic Medicine, University of Newcastle, Newcastle upon Tyne, UK

3. Chemical Engineering, Loughborough University, Loughborough, UK

4. Manchester Institute of Biotechnology, University of Manchester, Manchester, UK

5. Department of Surgery, University College London, London, UK

6. Intercytex Ltd & HairClone, Manchester, UK

7. Cell Therapy Manufacturing Development, Pfizer, Cambridge, UK

8. Standardisation Science, National Institute for Biological Standards and Control (NIBSC) a centre of the MHRA, South Mimms, Hertfordshire, UK

9. Department of Biomedical Sciences, University of Sheffield, Sheffield, UK

10. Asymptote (GE Healthcare), Cambridge, UK

11. Centre for Human Development, Stem Cells & Regeneration, University of Southampton, Southampton, UK

12. The Bioscience Engineering Group, University of Cambridge, Cambridge, UK

13. National Health Service – Blood & Transplant, Watford, UK

14. Fraunhofer-Institute for Biomedical Engineering, Sulzbach, Germany

15. Department of Molecular & Cellular Biotechnology/Nanotechnology, Saarland University, Saarbrücken, Germany

16. Department of Marine Sciences, Universidad Católica del Norte, Antafogasta/Coquimbo, Chile

Abstract

If the field of regenerative medicine is to deliver therapies, rapid expansion and delivery over considerable distances to large numbers of patients is needed. This will demand efficient stabilization and shipment of cell products. However, cryopreservation science is poorly understood by life-scientists in general and in recent decades only limited progress has been made in the technology of preservation and storage of cells. Rapid translation of new developments to a broader range of cell types will be vital, as will assuring a deeper knowledge of the fundamental cell biology relating to successful preservation and recovery of cell cultures. This report presents expert consensus on these and other issues which need to be addressed for more efficient delivery of cell therapies.

Publisher

Future Medicine Ltd

Subject

Embryology,Biomedical Engineering

Link

https://www.futuremedicine.com/doi/pdf/10.2217/rme-2017-0073

Reference68 articles.

1. Principles of Cryopreservation

2. Cryopreservation of Human Stem Cells for Clinical Application: A Review

3. Fundamental Points to Consider in the Cryopreservation and Shipment of Cells for Human Application

4. Vitrification in Tissue Preservation

5. Freeze/thaw stress induces organelle remodeling and membrane recycling in cryopreserved human mature oocytes

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