Pharmacogenomics in diverse practice settings: implementation beyond major metropolitan areas

Author:

Dorfman Elizabeth H1,Brown Trinidad Susan2,Morales Chelsea T3,Howlett Kevin4,Burke Wylie2,Woodahl Erica L3

Affiliation:

1. Institute for Public Health Genetics, University of Washington, Seattle, WA, USA

2. Department of Bioethics & Humanities, University of Washington, Seattle, WA, USA

3. Department of Biomedical & Pharmaceutical Sciences, University of Montana, Missoula, MT 59812, USA

4. Tribal Health & Human Services Department, Confederated Salish & Kootenai Tribes, St Ignatius, MT, USA

Abstract

Aim: The limited formal study of the clinical feasibility of implementing pharmacogenomic tests has thus far focused on providers at large medical centers in urban areas. Our research focuses on small metropolitan, rural and tribal practice settings. Materials & methods: We interviewed 17 healthcare providers in western Montana regarding pharmacogenomic testing. Results: Participants were optimistic about the potential of pharmacogenomic tests, but noted unique barriers in small and rural settings including cost, adherence, patient acceptability and testing timeframe. Participants in tribal settings identified heightened sensitivity to genetics and need for community leadership approval as additional considerations. Conclusion: Implementation differences in small metropolitan, rural and tribal communities may affect pharmacogenomic test adoption and utilization, potentially impacting many patients. Original submitted 3 September 2014; Revision submitted 3 December 2014

Publisher

Future Medicine Ltd

Subject

Pharmacology,Genetics,Molecular Medicine

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