Effects of Modified Dietary Fiber from Fresh Corn Bracts on Obesity and Intestinal Microbiota in High-Fat-Diet Mice

Author:

Geng Ningning1,Li Ying1,Zhang Yan2,Wang Hongjuan3,Song Jiangfeng123ORCID,Yu Lijun1,Wu Caie2

Affiliation:

1. Institute of Agro-Product Processing, Jiangsu Academy of Agricultural Sciences, Nanjing 210014, China

2. College of Light Industry and Food Engineering, Nanjing Forestry University, Nanjing 210037, China

3. College of Food Science and Technology, Nanjing Agricultural University, Nanjing 210095, China

Abstract

The effects of insoluble dietary fiber from fresh corn bracts modified by dynamic high-pressure micro-fluidization (DHPM) on the pathological characteristics of obesity, intestinal microflora distribution and production of short-chain fatty acids in high-fat-diet C57BL/6 mice were evaluated. The results show that the DHPM-modified dietary fiber from fresh corn bracts significantly reduces weight gain, insulin resistance and oxidative damage caused by a high-fat diet, and promotes the production of SCFAs, especially acetic acid, propionic acid and butyric acid. These modified dietary fibers also change the proportion of different types of bacteria in the intestinal microflora of mice, reduce the ratio of Firmicutes and Bacteroidota and promote the proliferation of Bifidobacteriales. Therefore, the DHPM-modified dietary fiber from fresh corn bracts can be used as a good intestinal microbiota regulator to promote intestinal health, thereby achieving the role of preventing and treating obesity.

Funder

Key Research and Development Program (Modern Agriculture) of Dantu District, Zhenjiang City, Jiangsu Province

Publisher

MDPI AG

Subject

Chemistry (miscellaneous),Analytical Chemistry,Organic Chemistry,Physical and Theoretical Chemistry,Molecular Medicine,Drug Discovery,Pharmaceutical Science

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