Assessing the Influence of COVID-19 Vaccination Coverage on Excess Mortality across 178 Countries: A Cross-Sectional Study-Reference-Cited by-同舟云学术

Assessing the Influence of COVID-19 Vaccination Coverage on Excess Mortality across 178 Countries: A Cross-Sectional Study

Published:2023-07-28 Issue:8 Volume:11 Page:1294
ISSN:2076-393X
Container-title:Vaccines
language:en
Short-container-title:Vaccines

Author:

Mendoza-Cano Oliver¹^ORCID,Trujillo Xóchitl²^ORCID,Huerta Miguel²^ORCID,Ríos-Silva Mónica³^ORCID,Guzmán-Esquivel José⁴^ORCID,Lugo-Radillo Agustin⁵^ORCID,Benites-Godínez Verónica⁶⁷,Bricio-Barrios Jaime Alberto⁸^ORCID,Cárdenas-Rojas Martha Irazema⁴^ORCID,Ríos-Bracamontes Eder Fernando⁹,Guzman-Solorzano Hannah Priscila⁸,Baltazar-Rodríguez Greta Mariana¹⁰,Ruiz-Montes de Oca Valeria¹¹,Ortega-Macías Vannya Marisol⁸,Ortega-Ramírez Ana Daniela¹²,Murillo-Zamora Efrén⁴^ORCID

Affiliation:

1. Facultad de Ingeniería Civil, Universidad de Colima, km. 9 Carretera Colima-Coquimatlán, Colima 28400, Mexico

2. Centro Universitario de Investigaciones Biomédicas, Universidad de Colima, Av. 25 de Julio 965, Col. Villas San Sebastián, Colima 28045, Mexico

3. Centro Universitario de Investigaciones Biomédicas, CONAHCyT—Universidad de Colima, Av. 25 de Julio 965, Col. Villas San Sebastián, Colima 28045, Mexico

4. Unidad de Investigación en Epidemiología Clínica, Instituto Mexicano del Seguro Social, Av. Lapislázuli 250, Col. El Haya, Colima 28984, Mexico

5. CONAHCyT—Facultad de Medicina y Cirugía, Universidad Autónoma Benito Juárez de Oaxaca, Ex Hacienda Aguilera S/N, Carr. A San Felipe del Agua, Oaxaca 68020, Mexico

6. Coordinación de Educación en Salud, Instituto Mexicano del Seguro Social, Calzada del Ejercito Nacional 14, Col. Fray Junípero Serra, Nayarit 63160, Mexico

7. Unidad Académica de Medicina, Universidad Autónoma de Nayarit, Ciudad de la Cultura Amado Nervo, Nayarit 63155, Mexico

8. Facultad de Medicina, Universidad de Colima, Av. Universidad 333, Col. Las Víboras, Colima 28040, Mexico

9. Departamento de Medicina Interna, Hospital General de Zona No. 1, Instituto Mexicano del Seguro Social, Av. Lapislázuli 250, Col. El Haya, Colima 28984, Mexico

10. Instituto Tecnológico y de Estudios Superiores de Monterrey, Escuela de Medicina y Ciencias de la Salud, Campus Guadalajara, Av. Gral. Ramón Corona No. 2514, Colonia Nuevo México, Zapopan 45201, Mexico

11. Plantel Guadalajara, Escuela de Medicina, Universidad Cuauhtémoc, Av. del Bajío No. 5901, Col. Del Bajío, Zapopan 45019, Mexico

12. Programa de Doctorado en Ciencias Médicas, Facultad de Medicina, Universidad de Colima, Av. Universidad 333, Col. Las Víboras, Colima 28040, Mexico

Abstract

The COVID-19 pandemic has had a devastating impact on global health, necessitating urgent and effective strategies to mitigate its consequences. Vaccination programs have been implemented worldwide to combat virus transmission and reduce the disease burden. This study aimed to investigate the relationship between COVID-19 vaccination coverage and all-cause excess mortality in 178 nations during the first two years of the pandemic. Multiple regression analysis, after adjusting for life expectancy at birth, confirmed a significant association between higher vaccination coverage and lower all-cause mortality rates (β = −106.8, 95% CI −175.4 to −38.2, p = 0.002). These findings underscore the importance of vaccination campaigns in reducing overall mortality during the COVID-19 pandemic. Evidence-based decision making and resource allocation can benefit from this information, facilitating the optimization of vaccination strategies for maximal impact on mortality reduction. Further research and continuous monitoring are crucial to understanding the long-term effects of vaccination coverage on population health in the ongoing pandemic.

Publisher

MDPI AG

Subject

Pharmacology (medical),Infectious Diseases,Drug Discovery,Pharmacology,Immunology

Link

https://www.mdpi.com/2076-393X/11/8/1294/pdf

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