1. Department II of Internal Medicine, Faculty of Medicine and University Hospital Cologne, University of Cologne, 50931 Cologne, Germany
2. Institute of General Practice, Faculty of Medicine and University Hospital Cologne, University of Cologne, 50931 Cologne, Germany
3. Center of Pharmacology, Faculty of Medicine, University Hospital of Cologne, University of Cologne, 50931 Cologne, Germany
4. Faculty of Medicine, University Clinic Hamburg Eppendorf, 20251 Hamburg, Germany
5. Faculty of Medicine, University of Gießen, 35392 Gießen, Germany
6. Medical Department B of Internal Medicine, Brandenburg Medical School, University Hospital Ruppin-Brandenburg, 16816 Neuruppin, Germany
7. Institute of Medical Statistics and Computational Biology, Faculty of Medicine, University Hospital Cologne, University of Cologne, 50931 Cologne, Germany
8. Ageing Clinical Research, Department II of Internal Medicine and Center for Molecular Medicine Cologne, Faculty of Medicine and University Hospital Cologne, University of Cologne, 50931 Cologne, Germany
9. Cologne Excellence Cluster on Cellular Stress-Responses in Aging-Associated Diseases (CECAD), University of Cologne, 50931 Cologne, Germany